孕早期体力勾当与怀胎期糖尿病干系的行列研究

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冯雅慧, 湛永乐, 吕嬿, 吴散散, 王雅文, 蔡姝雅, 石英杰, 陈云利, 马良坤, 江宇. 孕早期体力勾当与怀胎期糖尿病干系的行列研究[J]. 中华风行病学杂志, 2020, 41(6): 829-833

Feng Yahui, Zhan Yongle, Lyu Yan, Wu Sansan, Wang Yawen, Cai Shuya, Shi Yingjie, Chen Yunli, Ma Liangkun, Jiang Yu. Associations between physical activities and gestational diabetes mellitus in the first trimester of pregnancy[J]. Chinese Journal of Epidemiology, 2020, 41(6): 829-833.

孕早期体力勾当与怀胎期糖尿病干系的行列研究

冯雅慧1 , 湛永乐1 , 吕嬿2 , 吴散散1 , 王雅文1 , 蔡姝雅1 , 石英杰1 , 陈云利1 , 马良坤2 , 江宇1     

1. 中国医学科学院/北京协和医学院大众卫生学院, 北京 100730;
2. 中国医学科学院/北京协和医学院北京协和医院妇产科, 北京 100730

收稿日期: 2019-09-14

基金项目: 中国医学科学院医学与康健科技创新工程(2016-I2M-1-008);中央高校根基科研业务费专项(3332018019)

通信作者: 江宇, Email:jiangyu@pumc.edu.cn

摘要: 目的 前瞻性地探究北京地区孕妇总体力勾当和差别范例体力勾当与怀胎期糖尿病(gestational diabetes mellitus,GDM)的干系。要领 以中国孕产妇行列研究·协和项目中的909名孕妇为研究东西,回收孕期身体勾当问卷(pregnancy physical activity questionnaire,PPAQ)观测孕早期家务照顾、职业勾当、举动熬炼和交通勾当,并随访收集研究东西GDM诊断环境。回收非条件多因素logistic回归举办关联性阐明。功效 共206名孕妇(22.7%)诊断为GDM,调解年龄、孕前BMI、糖尿病家属史和其他种别体力勾当等因素后,logistic回归功效显示,对比于孕早期家务照顾较低程度的孕妇,中等程度的孕妇GDM产生风险较低(OR=0.654,95% CI:0.436~0.980);对比于不介入举动熬炼的孕妇,举动熬炼达标的孕妇GDM产生风险较低(OR=0.518,95% CI:0.287~0.934);总体力勾当、职业勾当和交通勾当与GDM的产生无关。结论 孕早期举动熬炼和家务照顾是GDM的影响因素,鼓励孕妇提高孕早期举动熬炼程度、从事适度家务照顾大概有助于防范GDM。

要害词: 怀胎期糖尿病    体力勾当    行列研究    

Associations between physical activities and gestational diabetes mellitus in the first trimester of pregnancy

Feng Yahui1 , Zhan Yongle1 , Lyu Yan2 , Wu Sansan1 , Wang Yawen1 , Cai Shuya1 , Shi Yingjie1 , Chen Yunli1 , Ma Liangkun2 , Jiang Yu1     

1. School of Public Health, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China;
2. Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China

Corresponding author: Jiang Yu, Email:jiangyu@pumc.edu.cn.

Fund program: CAMS Innovation Fund for Medical Sciences (2016-I2M-1-008); Fundamental Research Funds for the Central Universities (3332018019)

Abstract: Objective To prospectively explore the associations between total and different types of physical activities and gestational diabetes mellitus (GDM) in the first trimester of pregnant women, in Beijing. Methods Data of 909 participants from the Chinese Pregnant Women Cohort study were extracted and studied. Four types of physical activities, including household/care-giving, occupational, sports/exercise and outdoor ways of transportation (walking/cycling/E-biking) in early pregnancy were studied by using the pregnancy physical activity questionnaire (PPAQ). All the participants were followed up and related data on GDM collected. Logistic regressions were conducted for data analysis on the associations of interests. Results A total of 206 pregnant women (22.7%) were diagnosed with GDM. After adjusting for age, pre-pregnancy BMI, family history of diabetes and other types of physical activities, results from the logistic regression showed that women with moderate level of household/care-giving activities were with the lower odds on GDM (OR=0.654, 95%CI: 0.436-0.980). Women who had met the guideline of exercise were less likely to have GDM (OR=0.518, 95%CI: 0.287-0.934). There was no significant association appeared between total physical, occupational and outdoor ways of transportation (walking/cycling/E-biking) activities with GDM. Conclusions Sports/exercise and household/care-giving activities in early pregnancy appeared important on GDM prevention. Pregnant women are encouraged to wisely arranging their sports/exercise activities and engaging in moderate household/care-giving activities in the first trimester of pregnancy, to prevent GDM.

Key words: Gestational diabetes mellitus    Physical activity    Cohort study    

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